Nov 03 2025

Alzheimer’s might be powered by a broken sleep-wake cycle

Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of genes turn on and off. This disruption, triggered by amyloid buildup, scrambles normal gene timing in microglia and astrocytes—cells vital for brain maintenance and immune defense.

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Nov 03 2025

A gene from 100-year-olds could help kids who age too fast

Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By introducing this supercentenarian gene into Progeria-affected cells and mice, researchers restored heart function, reduced tissue damage, and slowed aging symptoms. The discovery opens the door to new therapies inspired by the natural biology of long-lived humans—possibly reshaping how we treat both rare diseases and normal aging.

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Nov 03 2025

A gene from 100-year-olds could help kids who age too fast

Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By introducing this supercentenarian gene into Progeria-affected cells and mice, researchers restored heart function, reduced tissue damage, and slowed aging symptoms. The discovery opens the door to new therapies inspired by the natural biology of long-lived humans—possibly reshaping how we treat both rare diseases and normal aging.

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From Science Daily • • 0

Nov 03 2025

A gene from 100-year-olds could help kids who age too fast

Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By introducing this supercentenarian gene into Progeria-affected cells and mice, researchers restored heart function, reduced tissue damage, and slowed aging symptoms. The discovery opens the door to new therapies inspired by the natural biology of long-lived humans—possibly reshaping how we treat both rare diseases and normal aging.

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Nov 01 2025

Scientists just shattered a major exercise myth

New research from Australia overturns the old idea that exercise “uses up” heartbeats. It shows that fitter people actually use fewer total heartbeats each day thanks to their lower resting heart rates, even when accounting for workouts. Athletes’ hearts beat around 10% less daily, saving over 11,000 beats per day compared to sedentary people. This efficiency not only signals cardiovascular fitness but also translates to longer life expectancy and lower disease risk.

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