‘Subclinical’ left ventricular abnormalities portend lower survival, breathlessness in SSc

Patients with systemic sclerosis who demonstrate left ventricular abnormalities, either overt or “subclinical,” have poorer survival and increased shortness of breath, according to data published in Seminars in Arthritis and Rheumatism.
The subclinical abnormalities were assessed via an advanced measure of subtle left ventricular systolic dysfunction — LV global longitudinal strain (LV-GLS) — suggesting that a less advanced measure — LV ejection fraction (LV-EF) — may not be sensitive enough to pick up clinically important cardiac dysfunction among patients

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