Systematic Review of Outcomes and Patient Experience with Virtual Care in Rheumatoid Arthritis

Abstract Objective To conduct a systematic review on patient outcomes of virtual care compared to conventional care in rheumatoid arthritis (RA) including disease activity and patient experience. Methods A systematic search of MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials was performed from database inception to 03/19/2020. Observational and randomized controlled trials (RCTs) describing the use of RA virtual care supplanting conventional visits and reporting on disease activity and/or patient experience were included. A narrative synthesis of results was conducted as a meta‐analysis was not possible due to heterogeneity of study designs and outcome reporting. Results 352 studies were identified, and 6 were selected for final inclusion: 3 were RCTs and 3 were observational studies. Disease activity and patient experience were comparable between virtual and conventional care models. In addition, one RCT found no difference in observed outcomes between virtual care delivered by a rheumatologist and by a rheumatology nurse. Virtual care was found to have additional benefits for improved treatment adherence, maintenance of functional status, and quality of life. The overall risk of bias was low in 2/3 RCTs, but high in the observational studies. Study quality was limited by incomplete data reporting, lack of sample size justification and sufficient timeframe to assess objectives. Conclusions There is limited evidence that virtual RA care is an acceptable alternative to conventional care, maintaining comparable patient outcomes and experience of care. Additional research into effective implementation strategies and long‐term health system and patient outcomes of virtual care are needed. Significance and Innovations: There is a paucity of research in the use of virtual care for rheumatology, especially describing the ability of virtual care modalities to supplant in person visits. Virtual care for rheumatoid arthritis (RA) management appears in the short term to provide equivalent control of disease activity and good patient experience compared to conventional follow‐up strategies. Future studies should evaluate the long‐term impacts of virtual care on RA outcomes and health service utilization.

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